Anti-inflammatory diet and venous thromboembolism: Two prospective cohort studies

Background and aimsInflammation has been revealed to facilitate thrombogenesis increase the risk of venous thromboembolism (VTE). However, limited data are available on association between anti-inflammatory diet incident VTE. We conducted a cohort analysis examine this further whether is modified by smoking status, trigger systemic inflammation.Methods resultsWe used from two cohorts including 81,507 middle-aged older Swedish adults without previous VTE at baseline. An empirically validated index (AIDI), based 12 foods with potential 5 pro-inflammatory potential, was employed estimate diet. Hazard ratios (HRs), corresponding 95% confidence intervals (CIs), were estimated Cox proportional hazards regression models. During mean follow-up 17.8-years, 5241 cases diagnosed. Compared individuals in lowest quartile AIDI (score ?4), those highest ?8) had 9% (95% CI, 0–17%) lower The inverse observed current past smokers (HR extreme quartiles, 0.80, 0.70–0.91) but not never (HR, 1.03, 0.91–1.17). French fries per serving, 1.33, 1.06, 1.67) no other included associated VTE.ConclusionThe study suggests that consumption high may play role prevention smokers.